Researchers have published a new study looking at the influence of prebiotic – gum acacia (GA) on the intestinal microbiota in rats with adenine-induced chronic kidney disease (CKD). There is evidence to suggest a bidirectional relationship between microbiota and CKD. The kidneys filter the flood, removing wastes and toxins, allowing them to be expelled through urine.
Chronic kidney disease is a condition where one or both kidneys fail entirely or partially. There is no cure for the condition, except for organ transplant.
Researchers said the work suggest that GA supplementation has a beneficial role in treating CKD. The GA increases the production of butyrate, as well as its anti-inflammatory, antioxidant capacity and anti-nitrosative properties. The rats were randomly distributed into four equal groups. One group was the control, other received the adenine, another received the GA and another received adenine plus GA groups.
They found Actinobacteria, Proteobacteria, Tenericutes and Verrucomicrobia
bacteria was increased in adenine-induced CKD. The GA treatment successfully reversed those levels in the rodents.
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